02/19/08

Dr K.R. Haylett

Papers and presentations

The following papers can be downloaded care of ( the Institute of Physics Publishing - www.iop.org and the IEE www.iee.org ):

Haylett,K.R., Globe, J., Smythe, A. ,Vales, P., Automatic analysis of ambulatory oesophageal manometry, 3rd joint IPEM/AGIP GI Physiological Measurement Meeting, York, December 2007.

Haylett, K.R., Chan, A., Globe,J., Smythe, A.,Vales, P., and R F McCloy, Using kohonen self organising feature maps for the analysis of ambulatory oesophageal manometry, 3rd International seminar on Medical Applications of Signal Processing, IEE, 3-4th November, 2005.

Haylett, K.R., Vales, P., and McCloy, R.F., The classification of oesophageal 24-hour pH measurements using a Kohonen self-organising feature map. Physiological Measurements, 2004. 2004. 25: 709-719.

Haylett, K.R., Vales, P., Lee, S.H., and McCloy, R.F., A pH-mucosa area unit of measure to consider morphology of the oesophagus when evaluating oesophagitis. Physiological Measurements, 2003. 24: 879-890.

Haylett, K.R., Vales, P., and McCloy, R.F., An investigation into the spatial relationship between complexity and motility within the oesophagus. Physiological Measurements, 1998. 19: 463-479.

Others

Ballester, P., The ergonomic evaluation and human-centred design approach to robotic systems in minimal invasive surgery, MD Thesis, Faculty of Medicine, University of Manchester, 2007, Research Tutor Haylett, K. R.,

Udani, R.D., and Haylett, K.R. et al. Writing up your research, SBMJ, 2007.15(November):406-408

Udani, S.D., and Haylett, K.R., et al. Peer review: it's not personal, SBMJ, 2007.15(March):96-97

Selvanathan, S.K., Haylett K.R., et al. The art of the abstract , SBMJ, 2006.14(February):70-71

Udani, S.D., and Haylett, K.R., The road to research, SBMJ, 2005.13(November):420-422

Haylett,K.R., Viewpoint: Health of the nation, what is a clinical technologist? Engineering and Technology Careers, IET, 2006:7

Udani, S.D., Correlation between oesophageal diameter, patient age,
oesophagitis and pH measurements, Sundip, July 2003,Research Tutor Haylett, K. R.,

Professional reports

If you are interested in 'Clinical Technologist' registration you may be interested in the reports I have made for the IET and IEE (follow IET and IEE links ) and for the latest open meeting with the NHS Chief Scientific Officer regarding this subject (follow this Link).

PhD and MSc - Readers Guide

The files can be downloaded from this site using the links below.

	The files are in the adobe format. A reader can be downloaded from www.adobe.com.
	All figures and tables are cross referenced in the text with hyper-links
	The Adobe table of contents allows the document to be easily negotiated
	This work is fully copyrighted and details of the copyright are included within each thesis
	The files will allow you to view and print them but not to select, or copy. Should you require further information, or wish to use the images contained within the document. please contact me.

Overview

This research started with the development of a system combining manometry and video fluoroscopy to enable a more detailed analysis of oesophageal manometry data. The first stages of the work were submitted as an MSc in 1996. Although fluoromanometry has been previously carried out using perfusion based manometry systems the goal was to develop a system that could be used in every day clinical practice using miniature strain gauge based manometry system and digital video recording.

This was followed by further developments of the system and a clinical study of fluoromanometry data from 25 patients, this formed the core of the research presented as a PhD thesis in 2000. This work included looking at mechanisms of modelling the system of excitation of the oesophagus and examining the complexity of the signals and information gained from the study. It also includes some simple modelling examining the parameters that need to be measured to quantify acid clearance, levels and swallowing efficiency. The thesis finishes with an examination of some new techniques that may be useful in future oesophageal and GI studies

Notes to readers

I would be grateful for any comments regarding the results and work presented here. It is of note that there is little evidence of medical engineers and physical scientists being involved in GI studies with most research coming from a clinical perspective. The work presented here, although involving a collaboration with clinicians, has followed a more medical engineering based direction of study. It is hoped that this will be of interest to both clinicians and medical engineers and they will be able to follow the arguments and details presented.

I would like to take this opportunity to thank my supervisor during this work Mr Rory. F. McCloy of the University Department of Surgery, Dr S H Lee of the Radiology Department and finally but not least Mrs P Vales, Head of the GI Investigation Unit. All of whom are based at the Manchester Royal Infirmary, Manchester, UK.

I would also like to thank Janssen–Cilag UK for their sponsorship of this research.

Much of the work presented has ultimately involved a collaboration of all these people.

Ph.D. - Oesophageal motility: A study of the transport mechanism of the oesophagus using fluoromanometry,nonlinear analysis and oesophageal modeling

M.Sc. Combined oesophageal manometry and video fluoroscopy